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Timeline

2009

  1. Jun 22

    President Obama signs the FAMILY SMOKING PREVENTION AND TOBACCO CONTROL ACT in a Rose Garden ceremony.

  2. Jun 10

    The Senate votes overwhelmingly to impose federal regulation on cigarettes and other forms of tobacco, passing the landmark FAMILY SMOKING PREVENTION AND TOBACCO CONTROL ACT.

  3. May 22

    The U.S. Court of Appeals for the District of Columbia Circuit largely upholds the honorable Gladys Kesslers landmark 2006 ruling, however, the appeals court rejected the governments bid to impose other remedies, including a request that the tobacco industry be forced to fund a national smoking-cessation program.

2008

2007

2006

  1. Aug 17

    USA v. PHILIP MORRIS. Federal District Court Judge Gladys Kessler, ruling for the United States District Court for the District of Columbia, imposes strict new limitations on tobacco marketing.

2005

  1. Jul 6

    Article Censorship by a tobacco company, by Herbert Barry III, is published online by Psychopharmacology.

  2. Jan 6

    DeNoble gives written testimony on behalf of plaintiffs in USA v. PHILIP MORRIS.

2004

  1. Sep 21

    Trial begins for USA v. PHILIP MORRIS.

  2. May 18

    A five-judge appeals court unanimously reverses Figueroas 10-02-02 order to vacate the $1.25 billion arbitration award to Ellis Private Counsel a/k/a Castano Litigation Group and the full award is reinstated.

2003

2002

  1. Sep 25

    New York State Supreme Court Judge Judge Nicholas Figueroa throws out a $1.25 billion legal fee the largest issued out of the 1998 nationwide settlement of state litigation against the tobacco industry awarded to the lawyers who handled a private attorney general’s action in California, saying the amount is irrational.

  2. Jul 15

    Tobacco Lawsuit Fee: $1.25 Billion in Los Angeles Times, by Henry Weinstein.

2001

  1. Dec 11

    Wendell Gauthier dies of liver cancer at his home in Metairie. He was 58.

2000

1999

  1. Sep 22

    The Department of Justice files a civil lawsuit against the major U.S. Tobacco companies.

  2. Jan 19

    During President Clintons State of the Union address, he announces that the DOJ shall file a civil lawsuit against the tobacco industry.

1998

  1. Nov 16

    The MASTER SETTLEMENT AGREEMENT is announced between state Attorneys General and tobacco companies to settle lawsuits.

  2. Jun 17

    The McCain bill is effectively killed by a 53-to-46 roll-call vote in the senate.

  3. May 19

    Senator McCain announces the provisions in the manager’s amendment to the National Tobacco Policy and Youth Smoking Reductions Act.

  4. Apr 24

    Article Tobacco: A Philip Morris Overseas Lab Stirs Attention, by Suein L. Hwang and Milo Geyelin, in Wall Street Journal.

  5. Feb 5

    Article Documents Indicate Strategy of Targeting Teen Smokers, by John Schwartz, in The Washington Post.

  6. Jan 29

    PM chairman Geoffrey Bible and other tobacco CEOs testify before the House Commerce Committee regarding Clintons opposition to the proposed settlement to end lawsuits by all 50 states.

  7. Jan 26

    DeNoble appears with Gray Davis in Sacramento where he speaks to legislators, committee staff and members of the press.

1997

  1. Nov 5

    Senator McCain, as Chairman of the Committee on Commerce, Science, and Transportation, introduces universal tobacco settlement act a/k/a McCain Bill.

  2. Jul 18

    U.S. Secretary of Health and Human Services Donna Shalala holds media availability at the White House following her meeting with tobacco industry whistleblowers, including DeNoble & Mele.

  3. Jun 20

    The Global Settlement Agreement is the first attempt at a settlement between the state attorneys general and the tobacco companies.

  4. May 1

    Tobacco companies offer a settlement that would include FDA regulation, money for anti-smoking campaigns, and bans on vending machines and outdoor advertising.

  5. Apr 20

    According to New York Times article “A Tangled Web of Factors Led to Tobacco Talks, by Barry Meier, the global settlement talks resume today in Chicago.

  6. Apr 17

    New York Times article “2 Top Cigarette Makers Seek Settlement, by John M. Broder, confirms that the tobacco industry has initiated negotiations.

  7. Jan 15

    Ellis/Castano amend their complaint to add then-Lieutenant Governor Gray Davis, thus becoming the Davis/Ellis case.

1996

  1. Oct 23

    Article 1972 memo at Philip Morris promotes high of nicotine, by Gail Appleson, in Chicago Sun-Times.

  2. Aug 21

    Gary Light and Tom Doyle receive summons for civil case MARK DEAN v. GARY DEAN LIGHT AND JOHN DOE.

  3. Aug 13

    Article Justice Dept. Clears FDA Aide Accused of Lying to Hill Panel, by John Schwartz, in The Washington Post.

  4. Jul 24

    ELLIS, ET AL. v. R. J. REYNOLDS TOBACCO CO. is filed in California Superior Court in San Diego County.

  5. Jun 1

    Article All 7 Tobacco Executives in Perjury Probe Have Quite the Industry, by Myron Levin, published Los Angeles Times.

  6. May 23

    The CASTANO case is decertified by U.S. Court of Appeals for the Fifth Circuit.

  7. Apr 2

    Congressman Joe Barton writes letter to Janet Reno and David Kessler, accusing Mitch Zeller of perjury.

  8. Mar 18

    FDA releases written statement from William A. Farone, Ph.D. re: “The manipulation and control of nicotine and tar in the design and manufacture of cigarettes: a scientific perspective.

  9. Mar 14

    New York Times article Tobaccos Broken Ranks: The Overview; Industry Split By Major Deal In Tobacco Suit, by Barnaby J. Feder.

  10. Mar 12

    The Castano plaintiff lawyers settle with Liggett Group.

  11. Feb 16

    Republican governor Kirk Fordice directs attorneys for the office of Governor to file suit in the Mississippi Supreme Court to challenge Attorney General Michael C. Moores representation of Medicaid.

1995

  1. Oct 18

    Article Fine-Tuning Marlboro, by Alix M. Freedman, appears in The Wall Street Journal.

  2. Sep 26

    DeNoble testifies before the Massachusetts State Senates Joint Committee on Health Care on behalf of its pending tobacco disclosure legislation.

  3. Aug 31

    Article Ex-Philip Morris Scientist To Be in Antismoking Ad appears in Wall Street Journal.

  4. Jul 12

    Financial world ranks Marlboro the world’s no. 2 most valuable brand behind Coca-Cola.

  5. Jun 8

    Article Documents Disclose Philip Morris Studied Nicotines Effect on Body, by Philip J. Hilts and Glenn Collins, in The New York Times.

  6. Feb 26

    Article Tobacco Lawsuit Phones Smoking: Class Action is the Biggest Ever, by Jeffrey Meitrodt, in Times-Picayune.

  7. Feb 18

    Article Judge OKs massive suit against tobacco companies, by David Talbot, in The Boston Herald.

  8. Feb 17

    Castano is conditionally certified as a class action the District Court.

1994

  1. Jun 30

    DeNobles written response to Bliley request for additional answers concerning the issue of tobacco and health.

  2. Jun 22

    Article Cigarette Company Developed Tobacco With Stronger Nicotine, by Warren E. Leary, in The New York Times.

  3. Jun 21

    Thomas Bliley gives closing statement at Subcommittee on Health and the Environments Hearing on the Oversight of Tobacco Products, with FDA Commissioner David Kessler presenting additional evidence of nicotine manipulation.

  4. Jun 17

    Article Cigarette Safety Research Was Started Then Stopped, by Philip J. Hilts, in The New York Times.

  5. Jun 16

    Article Cigarette Makers Debated the Risks They Denied, by Philp J. Hilts, in The New York Times.

  6. May 26

    Thomas Bliley gives opening statement at Subcommittee on Health and the Environments Hearing on the Oversight of Tobacco Products, with president and CEO of the Council for Tobacco Research, appearing before the subcommittee.

  7. May 24

    Article Mississippi insists that tobacco giants pay for their sins , by Michael Janofsky, in The Houston Chronicle.

  8. May 23

    Attorney General Michael C. Moore files THE STATE OF MISSISSIPPI v. AMERICAN TOBACCO et. al., is filed in the Chancery Court of Jackson County, Mississippi (Case No. 94-1429).

  9. May 21

    Article 51 Law Firms to Plead Tobacco Suit, by Bill Voelker, in Times-Picayune.=

  10. May 16

    Brown & Williamson is granted a Kentucky state court injunction, requiring Waxman and senator Ron Wyden to allow B&W to review company documents in their possession.

  11. May 13

    Article Lawyers for tobacco firm hid research, by Doug Levy, in USA Today.

  12. May 12

    Article Method to Produce Safer Cigarette Was Found in 60s, but Company Shelved Idea, by Philip J. Hilts, is published in The New York Times.

  13. May 7

    Article Tobacco Company Was Silent on Hazards, by Philip J. Hilts, is published in The New York Times.

  14. Apr 29

    Article Scientists Say Cigarette Company Suppressed Findings on Nicotine, by Philip J. Hilts, published in The New York Times.

  15. Apr 28

    DeNoble and Mele appear before the subcommittee.

  16. Apr 27

    DeNoble issues a written statement in advance of his 4-28-94 appearance before the subcommittee.

  17. Apr 26

    Article U.S. Agency Suggests Regulating Cigarettes as an Addictive Drug, by Philip J. Hilts, published in The New York Times.

  18. Apr 25

    Waxman writes to Victor inviting him to testify before the committee.

  19. Apr 25

    William Campbell writes letter to Henry Waxman, agreeing to waive Paul Meles confidentiality agreement so that he can testify before the subcommittee.

  20. Apr 20

    Article Bullies in Congress will hardly stop with cigarettes, by Philip Terzian, in Rocky Mountain News.

  21. Apr 14

    The seven top tobacco CEOs appear before the Subcommittee on Health and the Environment. Philip Morris President and CEO William I. Campbell agrees to release DeNoble from his confidentiality agreement so that he can testify.

  22. Apr 14

    Article 81 Tobacco Study Discussed Raising Levels of Nicotine, by Philip J. Hilts, in The New York Times.

  23. Apr 1

    Article Philip Morris Blocked 83 Paper Showing Tobacco Is Addictive, Panel Finds, by Philip J. Hilts, is published in The New York Times.

  24. Mar 31

    Waxman holds press conference, revealing Victor and his research, and inviting top tobacco CEOs to testify before the subcommittee.

  25. Mar 31

    PMUSA issues statement in response to Waxmans allegations.

  26. Mar 30

    Castano Litigation Group issues TEMPORARY RESTRAINING ORDER WITHOUT NOTICE AND ORDER TO SHOW CAUSE WHY PRELIMINARY INJUCTION SHOULD NOT ISSUE in the United States District Court for the Eastern District of Louisiana.

  27. Mar 29

    Wendell Gauthier files CASTANO et al v. AMERICAN TOBACCO.

  28. Mar 25

    Kessler appears before the Oversight Hearing on Tobacco Products Before the Subcommittee on Health and the Environment of the House Committee on Energy and Commerce.

  29. Mar 24

    Kessler writes follow-up letter to Bliley regarding his 03-18-94 request.

  30. Mar 24

    Philip Morris announces a $10 billion libel suit against ABC and against both the producer and reporter on the Day One story.

  31. Mar 24

    PMUSA president William Campbell writes follow-up letter to members of Congress announcing lawsuit.

  32. Mar 23

    Following phone conversation with Mitch Zeller, Herbert Barry writes detailed follow-up letter outlining various manuscripts submitted by Victor DeNoble for publication in PSYCHOPHARMACOLOGY.

  33. Mar 19

    DeNoble has follow-up meeting with Kessler and Tobacco Working Group.

  34. Mar 18

    Conference call with Mele and Mitch Zeller, David Kessler, Tom & Gary.

  35. Mar 18

    Thomas Bliley writesletter to Kessler, requesting all evidence in the FDAs possession regarding the intent of cigarette manufacturers with respect to the presence of nicotine in cigarettes.

  36. Mar 17

    Kessler writes letter to William Campbell and requests that FDA representatives be allowed to meet with members of your research, scientific, technical, and production staffs and to review relevant information.

  37. Mar 17

    Light & Doyle meet Paul (codenamed Cigarette Junior) at his laboratory.

  38. Mar 16

    Light & Doyle phone Paul Mele at the armed forces radio biology research institute in Bethesda, MD.He was willing to talk.

  39. Mar 15

    Gary Light & Tom Doyle meet with Victor at the Christiana Hilton in Newark, Delaware, then update the FDAs Tobacco Working Group.

  40. Mar 15

    A letter to the editor from Philip Morris President and CEO William I. Campbell is published in the New York Times.

  41. Mar 9

    DeNoble is discussed in status meeting with Kessler.

  42. Mar 8

    DeNoble first contacted by FDA Tobaco Working Group.

  43. Mar 7

    Letter from C.O.S.H. to Kessler.

  44. Mar 4

    FDAs Tobacco Working Group holds its second strategy meeting.

  45. Mar 3

    PMUSA president William I. Campbell sends letter to members of Congress and also shares with all PMUSA employees regarding DAY ONE broadcast.

  46. Feb 28

    ABC News airs DAY ONE episode titled Smoke Screen.

  47. Feb 28

    FDAs Tobacco Working Group holds its first strategy meeting.

  48. Feb 25

    FDA Commisioner David Kessler, responding to a petition asking FDA to regulate low-tar and low-nicotine cigarettes, writes letter to C.O.S.H. chairman Scott Ballin, stating that the Agency will consider the question of whether it has jurisdiction over nicotine-containing tobacco products.

1993

1992

  1. Oct 26

    Brown & Williamsons Research & Development department distributes a restricted competitive analysis of ammonia use in Marlboro cigarettes, PMS GLOBAL STRATEGY: MARLBORO PRODUCT TECHNOLOGY.

1991

1990

1989

1988

  1. May 3

    Health and Human Services Secretary Otis R. Brown, MD, distributes Surgeon Generals report, THE HEALTH CONSEQUENCES OF SMOKING: NICOTINE ADDICTION, to President George H.W. Bush and members of Congress.

1987

1986

1985

1984

  1. Apr 9

    DeNoble and Mele begin formal outplacement proceedings, i.e. although theyll continue to be paid, this is their last official day of work.

  2. Mar 23

    Osdene discusses DeNoble with Fred Newman who reiterates the importance of VD and Mele leaving PM feeling well regarding business decision.

  3. Mar 22

    Philip Morris submits its first answers to CIPOLLONE plaintiffs interrogatories. Answers are prepared by Thomas Osdene and Jim Charles.

  4. Mar 22

    According to Osdenes handwritten notes, on this day he and Jim Charles, Ted Sanders, and Max Hausermann discuss closing down Victors lab ASAP.

  5. Mar 16

    Marc Edells law firm, Porzio, Bromberg & Newman Esqs. serve request that defendant Philip Morris produce designated documents and things on 04-23-84.

  6. Mar 7

    Memo from DeNoble to Cathy Ellis re: neurochemical basis of acetaldehyde’s behavioral effects.

  7. Feb 1

    Marc Edells law firm, Porzio, Bromberg & Newman Esqs. serve notice that, starting on 03-20-84, the plaintiffs will take the deposition upon oral examination of Philip Morris Incorporated.

  8. Jan 16

    Bob Pages handwritten comments regarding Directors Meeting include a comment by Fred Newman: less writing the better.

1983

  1. Oct 5

    DeNoble and Mele submit memorandum to Jim Charles entitled BEHAVIORAL EFFECTS OF TERMINATION OF CHRONICALLY ADMINISTERED NICOTINE-ACETALDEHYDE COMBINATIONS ON LEVER PRESSING MAINTAINED UNDER A FIXED RATIO SCHEDULE OF FOOD PRESENTATION IN RATS.

  2. Sep 6

    Victor submits memo to Jim Charles re: PROJECT 1610 BEHAVIORAL PHARMACOLOGY Objectives and Plans, 1984.

  3. Aug 30

    DeNoble writes to Dr. Herbert Barry to inform him that due to factors beyond my control, he must withdraw NICOTINE AS A POSITIVE REINFORCER IN RATS from consideration as a publication in PSYCHOPHARMACOLOGY.

  4. Aug 26

    DeNoble and Mele attend the American Psychological Associations 91st annual convention in Anaheim, CA.

  5. Aug 19

    Jim Charles handwritten note to Osdene re: NICOTINE AS A POSITIVE REINFORCER IN RATS: EFFECTS OF INFUSION DOSE AND FIXED-RATIO SIZE.

  6. Aug 2

    Marc Edells law firm, Porzio, Bromberg & Newman, Esqs., serve complaint to Philip Morris, Inc. re: CIPOLLONE vs. LIGGETT GROUP

  7. Aug 1

    CIPOLLONE vs. LIGGETT GROUP filed in the U.S. District Court for the District of New Jersey in Newark.

  8. Jul 27

    Shook Hardy & Bacon lawyer Patrick Sirridge writes to Newman, transmitting an analysis of DeNobles published literature, unpublished manuscripts, and in-press manuscripts.

  9. Jul 12

    This document listing info regarding a Coca-Cola patent to convert ethanol into acetaldehyde. The written comments from VP of Development and Research, Bob Seligman, underscore the fact that PM is monitoring acetaldehyde-related patents and production, with an aim to manufacture it themselves, and very excited about its capacity to be called natural.

  10. Jun 19

    Denoble promoted to Associate Senior Scientist.

  11. Jun 14

    DeNoble submits memorandum to Jim Charles regarding Prostration and Discrimination Tests.

  12. Jun 1

    Project 1610. BEHAVIORAL PHARMACOLOGY ANNUAL REPORT 1983, written by DeNoble and Mele.

  13. Mar 1

    Memo from Jim Charles to Osdene, recommending Victor for promotion from Research Scientist to Associate Senior Scientist.

  14. Jan 27

    Memo from Osdene to McDowell re: Smoking and Health, A Look Into The Future.

  15. Jan 10

    Hausermann approves manuscript for NICOTINE AS A POSITIVE REINFORCER IN RATS: EFFECTS OF INFUSION DOSE AND FIXED-RATIO SIZE for publication in SCIENCE.

1982

  1. Dec 22

    Memo from Holtzman to Hausermann re: hes approved NICOTINE AS A POSITIVE REINFORCER IN RATS: EFFECTS OF INFUSION DOSE AND FIXED-RATIO SIZE for publication, with proviso that Jim Charles will review text and improve where necessary.

  2. Dec 14

    DeNoble presentation RESEARCH OVERVIEW OF THE BEHAVIORAL PHARMACOLOGY LAB to Executive VP of Operations W.W. McDowell and senior management in NYC.

  3. Nov 9

    Victor and colleagues present informational content of NICOTINE AS A POSITIVE REINFORCER IN RATS: EFFECTS OF INFUSION DOSE AND FIXED-RATIO SIZE at MCV seminar “Behavioral Pharmacology of Nicotine”.

  4. Oct 25

    Memorandum from Hausermann to Lunsford in Manuscript Review Board re: Approval of Information for Presentation at a seminar at the Medical College of Virginia.

  5. Oct 19

    Memorandum from Hausermann to Holtzman: The attached abstract entitled NICOTINE AS A POSITIVE REINFORCER IN RATS: EFFECTS OF INFUSION DOSE AND FIXED-RATIO SIZE has been submitted to me for presentation at a seminar “Behavioral Pharmacology of Nicotine” sponsored by the Neuroscience Department, Medical College of Virginia, on November 8, 1982.

  6. Oct 1

    Revised manuscript for NICOTINE AS A POSITIVE REINFORCER IN RATS: EFFECTS OF INFUSION DOSE AND FIXED-RATIO SIZE

  7. Oct 1

    DeNobles manuscript for NICOTINE AS A POSITIVE REINFORCER IN RATS: EFFECTS OF INFUSION DOSE AND FIXED-RATIO SIZE is forwarded from Carol G. Lunsford to Senior VP Max Hausermann for his approval re publication in NATURE.

  8. Oct 1

    From Victors Performance Appraisal Form, covering his work from 9-1-81 to 9-1-82, signed by Jim Charles and Osdene

  9. Aug 12

    Biochemical Research Division Symposium for October 1982 is postponed until first quarter 1983.

  10. Aug 2

    In a memo to Jim Charles, DeNoble recommends promotion of Mele to the level of Research Scientist.

  11. Aug 1

    The abstract for BEHAVIORAL EFFECTS OF INTRAVENTRICULARLY ADMINISTERED (-)- NICOTINE ON FIXED RATIO SCHEDULES OF FOOD PRESENTATION IN RATS is published in the spring-summer 82 edition of PSYCHOPHARMACOLOGY.

  12. Jul 30

    Memo from Jim Charles: You are invited to attend a symposium entitled The Influence of Nicotine on Research Directions in Biochemistry to be held at the Lecture Hall on Wednesday, October 13, 1982. Topics include Nicotine as an Intravenously Delivered Positive Reinforcer: A Behavioral and Pharmacological Analysis, presented by DeNoble.

  13. Jul 20

    Victor submits memorandum to Jim Charles re PROJECT NUMBER 1610: BEHAVIORAL PHARMACOLOGY Objectives and Plans 1982-83.

  14. Jun 30

    Memorandum from Jim Charles to Osdene re: Topics for Richmond Meeting. Recommended topics for Behavioral Pharmacology Overview include Nicotine and Self-Administration and Nicotine and Dependency, with DeNoble as the suggested speaker for each.

  15. Jun 28

    Bob Pages and Judy Johns handwritten notes from Biochemical Division Project Leaders Meeting.

  16. Jun 23

    A for your review and early comments memorandum from Eichorn to Farone and Hausermann, et al, regarding NICOTINE AS A POSITIVE REINFORCER IN RATS: EFFECTS OF INFUSION DOSE AND FIXED-RATIO SIZE.

  17. Jun 14

    DeNoble submits (revised?) abstract for manuscript NICOTINE AS A POSITIVE REINFORCER IN RATS: EFFECTS OF INFUSION DOSE AND FIXED-RATIO SIZEto Manuscript Review Board for publication in NATURE.

  18. May 7

    Hausermann approves EFFECTS OF CHRONIC NICOTINE ADMINISTRATION AND ITS TERMINATION ON SCHEDULE-CONTROLLED BEHAVIOR IN RATS for publication in SCIENCE and presentation at upcoming annual meeting of Society of Neuroscience on 10-24-82.

  19. Apr 21

    Denoble and Mele submit BEHAVIORAL PHARMACOLOGY LABORATORY PROGRESS REPORT, covering 03-01-81 thru 03-01-82.

  20. Mar 19

    Abstract submitted to Manuscript Review Board for INFLUENCE OF BEHAVIORAL FACTORS IN THE DEVELOPMENT OF TOLERANCE TO (-)- NICOTINE re approval for publication in Journal of Pharmacology and Therapeutics during 1983 and presentation at American Psychological Associations annual meeting in August 1983.

  21. Mar 19

    DeNoble submits abstract for manuscript NICOTINE AS A POSITIVE REINFORCER IN RATS: EFFECTS OF INFUSION DOSE AND FIXED-RATIO SIZE (co-written with Mele and Frank Ryan) to Manuscript Review Board for publication in NATURE.

  22. Mar 8

    Memo from Eichorn to Hausermann re: EFFECTS OF CHRONIC NICOTINE ADMINISTRATION AND ITS TERMINATION ON SCHEDULE-CONTROLLED BEHAVIOR IN RATS has been reviewed by Manuscript Review Board and is recommended for publication in SCIENCE and presentation at Society of Neuroscience on 10-24-82.

  23. Feb 23

    Handwritten response from A.J. Kassman to Eichorns 02-23-82 for your review and early comment memo Sounds like were into the animal testing business. I think were getting on thin ice.

  24. Feb 22

    EFFECTS OF CHRONIC NICOTINE ADMINISTRATION AND ITS TERMINATION ON SCHEDULE-CONTROLLED BEHAVIOR IN RATS is submitted to Manuscript Review Board for approval re publication in SCIENCE and presentation at upcoming annual meeting of the Society for Neuroscience on 08-24-82. NOTE: THE ONLY VERSION I CAN FIND IS DATED MARCH 82.

  25. Jan 27

    Memo from Eichorn to DeNoble, advising him that the abstract of his manuscript ABSENCE OF DELETERIOUS BEHAVIORAL EFFECTS FOLLOWING WITHDRAWAL FROM CHRONIC NICOTINE ADMINISTRATION IN RATS has been reviewed by Hausermann and Directors and they have no problem with subject matter.

  26. Jan 8

    Handwritten memo from DeNoble to Jim Charles re: multiple phase filter that will remove many gas phase components from smoke.

  27. Jan 7

    DeNoble gives presentation on his research to New York management, detailing results of nicotine self-administration and acetaldehyde self-administration, together they make a supraadditive.

1981

  1. Dec 10

    Victor receives memo from Eichorn informing him that the manuscript BEHAVIORAL EFFECTS OF INTRAVENTRICULARLY ADMINISTERED (-)-NICOTINE ON FIXED RATIO SCHEDULES OF FOOD PRESENTATION IN RATS has been approved for publication in Journal of Pharmacology, Biochemistry and Behavior.

  2. Dec 8

    Handwritten notes by Pages from group meeting with staff involved with nicotine receptor program, including Abood, Mele, Dragan, Seligman, DeNoble, Dunn, Gullotta, and Seeman.

  3. Nov 16

    Paul Mele begins employment in Behavioral Research Lab as Research Scientist.

  4. Nov 12

    Eichorn memo to Hausermann and Directors re: manuscript approval for BEHAVIORAL EFFECTS OF INTRAVENTRICULARLY ADMINISTERED (-)- NICOTINE ON FIXED RATIO SCHEDULES OF FOOD PRESENTATION IN RATS.

  5. Nov 5

    Memo from Dunn to Osdene outlining the Behavioral Research Labs Plans and Objectives 1982, Dunn identifies DeNoble, Paul Mele showing up for the first time and Dragan as the three principals in the Behavioral Pharmacology group.

  6. Oct 18

    DeNoble and Carron present STUDIES ON THE EFFECTS OF INTRAVENTRICULAR INFUSIONS OF (-)- NICOTINE ON BEHAVIOR MAINTAINED UNDER FIXED-RATIO SCHEDULES, at the Society for Neurosciences annual meeting in Los Angeles, CA. The abstract is published in Society for Neuroscience Abstracts 7.

  7. Sep 10

    DeNobles Performance Appraisal Form, covering his work from 2-1-81 to 9-1-81, signed by Dunn and Osdene.

  8. Jul 10

    Paul C. Mele, Ph.D. accepts position as “Research Scientist” in the Behavioral Research department.

  9. Apr 7

    Memo from Seligman to Eichorn, approving abstract for STUDIES ON THE EFFECTS OF INTRAVENTRICULAR INFUSIONS OF (-)- NICOTINE ON BEHAVIOR MAINTAINED UNDER FIXED RATIO SCHEDULES (FR), for presentation at Society for Neuroscience, 1981 Annual Meeting.

  10. Mar 27

    DeNoble and Carron submit PROGRESS IN BEHAVIORAL PHARMACOLOGY LABORATORY, FOR PERIOD BEGINNING JUNE 80 THRU MARCH 81, to Dunn.

  11. Feb 12

    Handwritten note from C.H. ODonohue to Eichorn re: Do we want it known that we do animal studies?

  12. Feb 12

    In reply to note from Eichorn to Osdene and others, Walter Gannon (director of product development for Philip Morris Inc.) writes: Are we willing to publish results of studies performed in-house on intact animals? Richard Thomson replies: Since word of this work and similar stuff does appear to find its way outside the company anyway, publication may be preferable to suspicions. Need to get legal okay out of N.Y. B.J. Kosakowski to Eichorn: Longest abstract Ive seen. Im still doubtful on publishing rat projects.

  13. Jan 26

    Handwritten note from Paul Eichorn to Seligman concerning Manuscript for Presentation re: STUDIES ON THE EFFECTS OF INTRAVENTRICULAR INFUSIONS OF (-)- NICOTINE ON BEHAVIOR MAINTAINED UNDER FIXED RATIO SCHEDULES (FR).

  14. Jan 23

    DeNobles Performance Appraisal Form, covering his work from 5-1-80 to 5-1-81, signed by Dunn and Osdene.

  15. Jan 20

    Abstract for STUDIES ON THE EFFECTS OF INTRAVENTRICULAR INFUSIONS OF (-)- NICOTINE ON BEHAVIOR MAINTAINED UNDER FIXED RATIO SCHEDULES (FR), by DeNoble and Carron, submitted to the Manuscript Review Board.

1980

  1. Dec 23

    Memorandum from Dunn to Osdene re BEHAVIORAL RESEARCH ACCOMPLISHMENTS 1980. Includes overview of the Behavioral Pharmacology Program, written by DeNoble.

  2. Nov 26

    In a memo from Dunn to Osdene outlining his Plans and Objectives 1981, Dunn includes DeNobles Behavioral Pharmacology Program and lists the following planned studies: Nicotine Self-Administration; Nicotine-Induced Prostration Syndrome; Discrimination Studies (to evaluate nicotine analogues).

  3. Nov 3

    Memorandum from Osdene to Seligman re Status of Nicotine Program.

  4. Oct 20

    Memorandum from Jeffrey I. Seeman to Osdene re recent efforts in nicotine analogue synthesis and chemistry.

  5. Oct 14

    DeNoble and Carron submit a Progress Report for the Behavioral Pharmacology Program to Osdene, detailing how theyd begun a series of studies to evaluate nicotine and nicotine analogues.

  6. Sep 9

    Memorandum from Dunn to Osdene re 1600: Smoker Psychology progress report for August 80, includes update re DeNobles project The Discriminative Stimulus Properties of l-nicotine and Nicotine Analogues.

  7. Aug 18

    DeNoble and Carron submit memorandum to Dunn entitled Research Progress Concerning Discrimination and Prostration Studies.

  8. Jul 23

    DeNoble, Osdene, Dunn & Frank Ryan write memo to Seligman explaining the technique and purpose of self-administration studies.

  9. Jul 10

    Dunns monthly report for 1600: Smoker Psychology for June 1980, mentions that DeNobles working on two project.

  10. Jun 2

    Memorandum from Dunn to Osdene re: Behavioral Research Lab, Four Major Studies.

  11. May 12

    Dunns monthly report for 1600: Smoker Psychology project for April 1980, includes the first written abstracts by DeNoble.

  12. May 7

    Carolyn Levy and Lisa Carron submit memo to DeNoble re Discrimination Studies.

  13. Apr 24

    DeNoble submits memo to Dunn re Nicotine Program Behavioral Research Laboratory.

  14. Apr 1

    DeNoble starts work at PM and becomes project leader of the Behavioral Pharmacology Laboratory, previously known as the Comparative Psychology Program.

  15. Mar 21

    Memo from Dunn to Seligman, addressing lawyers concerns about in-house research on the psychopharmacology of nicotine.

  16. Feb 18

    Memo from Carolyn Levy & Lisa Carron to Dunn, outlining their Prostration Syndrome research with rats.

  17. Jan 21

    Memo from Dunn to Osdene re Behavioral Research Accomplishments 1979.

  18. Jan 7

    Memo from Dunn to Osdene re Plans and Objectives 1980.




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